Dr. Nunilo Cremades
Dept. of Chemistry, University of Cambridge
I received my Ph.D. in Biochemistry from the University of Zaragoza (Spain) with summa cum laude qualification, for my work in the group of Prof. Javier Sancho, where I gained a very broad experience in biophysics, specially protein folding andstability. During this period I published 11 research papers in leading international journals, being first author in 7 of them, and was main inventor in five patents (one Norwegian and four Spanish, all of them further extended to areas such as UE, USA, Japan and Canada). I also engaged in exciting projects as part of two enriching stays in the USA: with Prof. Ernesto Freire at the Johns Hopkins University, Baltimore and Prof. Paul S. Hoffman at theUniversity of Virginia, Charlottesville. I started my post-doctoral career in April 2008 at the Department of Chemistry of the University of Cambridge (UK), in the group of Prof. Chris Dobson, initially to develop a drug discovery research project in collaboration with a pharmaceutical company (work resulting in one US patent). In April 2009 I was awarded the renowned Human FrontiersScience Program (HFSP) Long-term Postdoctoral Fellowship to continue my work with Chris Dobson in Cambridge and undertake a challenging project on the study of amyloidogenic proteins implicated in neurodegenerative diseases. This work has resulted in 6 publications so far, being the most relevant that published in the prestigious journal Cell, where I am first author. My main current research focuses on the study of the molecular basis of amyloid-mediated toxicity in neurodegenerative diseases, specifically Parkinson’s disease, using state-of-the-art biological and biophysical techniques such as single-molecule fluorescence.