Patrick Lewis, PhD
Dept. of Molecular Neuroscience, Institute of Neurology
University College London
I’m a research fellow at the Institute of Neurology, part of University College London. I’ve been working on neurodegenerative diseases for over ten years, both here in the United Kingdom and in the United States, looking at what happens to brain cells in a dish when we introduce mutations that cause Alzheimer’s and Parkinson’s disease in humans. We’ve learned a huge amount in the last two decades, with a lot of this coming from finding out about rare genetic forms of these diseases. At the moment my research is focused on one of these genes – called LRRK2 (pronounced Lurk two) – which is probably the most common genetic cause of Parkinson’s disease, and my group is trying to understand how the mutant LRRK2 changes the way in which cells in the brain function causing them to die. You can read more about my research, and access some of the papers that my group has published, here.